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Image Search Results
Journal: PLoS ONE
Article Title: Direct administration of the non-competitive interleukin-1 receptor antagonist rytvela transiently reduced intrauterine inflammation in an extremely preterm sheep model of chorioamnionitis
doi: 10.1371/journal.pone.0257847
Figure Lengend Snippet: A. Endotoxin concentrations in amniotic fluid. Plots show median, 25th, and 75th percentile ranges of AF endotoxin concentrations at 24 hours post-administration as boxes and 5th to 95th percentile as error bars. *p < .05 vs. the Saline Group. n = 6–10 animals/group. AF, amniotic fluid; LPS, lipopolysaccharide. B. Cytokines/chemokine concentrations in amniotic fluid from 0 to 24 hours after either saline or LPS. A, amniotic fluid IL-1β, IL-8, MCP-1, and TNF-α concentrations. *p < .05 between the Saline Group and the LPS-treated Groups (LPS Group and LPS + rytvela Group). Plots show median, 25th, and 75th percentile ranges as boxes and 5th to 95th percentile as error bars. n = 4–8 animals/group. AF, amniotic fluid; LPS, lipopolysaccharide; ELISA, Enzyme-linked inmmunosorbent assay.
Article Snippet: Quantification of the cytokine IL-1 in amniotic fluid, cord blood at delivery, and fetal lung and IL-8 in amniotic fluid and cord plasma were measured by using a
Techniques: Saline, Enzyme-linked Immunosorbent Assay